UPDATES FAIL!!

last week i noticed WINDOWS DEFENDER DEFS have not been updated in 16 days
I opened WIN DEFENDOR to UPDATE THE DEFS
after few mins a small window popped up that read

Windows Defender was unable to complete the update:
0x80240022. The wrong diskette is in the drive. Insert %2
[Volume Serial Number: %3] into drive %1.


I went to CONTROL PANEL - AUTOMATIC UPDATES
ALL Tabs are GREYED OUT.

I did a search on MS SITE for ERROR #
0x8000A0046

1st site I used for
http://support.microsoft.com/?scid=kb;en-us;883821#
i tried MS update, windows update all to no avail. i searched for the error
# on MS SITE and did ALL the recommendations it said about changing security,
permissions, etc.

2nd site I used for
http://support.microsoft.com/kb/910338/

i got frustrated and quit.
today tried again. to NO AVAIL!


Can ANYONE at MS help get MY MACHINES UPDATED !
.