Securing company's laptop

Hi,
Im looking for a solution to make data stored on laptop more secure.
I wish to have soulution which let me to secure outlook data and
mydocument folder for few key users in company's network.
The main problem is that users whish is to pretend even computer
administrator (which is IT manager), to access the data, they want data
to be totally private for them.
Could anyone tell me what kind of solutions are in use for securing
CEO's computers ?

regards
Peter

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